This paper proposes the neural network self-tuning PID controller for the load frequency control of 2- areas power system, namely, the prompt convergence of frequency and tie-line power flow deviation. The neural network applied to computer simulation consists of neurons of two inputs, ten hiddens and tliree outputs layer. Neurons of two inputs layer receive the error and its change rate of the system and cutputs layer consists of three neurons for the parameters of the PID controller. The simulation results shows that the proposed neural network self-tuning PID controller is superior to conventional control t~:chniques(Optimal, PID) in dynamic response and control performance.