In this paper we have a concern on the Moore-Penrose inverse of two kinds of partitioned matrices of the form [V X] and [{{{{ {V atop {X} {{{{ {X atop { 0} }}] where V is symmetric. The Moore-Penrose inverse of the partitioned matrices can be reduced to be simpler forms according to some algebraic conditions. Firstly we investigate the representations of the Moore-Penrose inverses of the partitioned matrices under four al-gebraic conditions. Each condition reduces the Moore-Penrose inverses of the partitioned matrices under four al-gebraic conditions. Each condition reduces the Morre-Penrose inverse into some simpler form. Also equivalant conditions will be considered. Finally we will perform a simulation study to investigate which con-dition is the most important in the sense that which condition occurs the most frequently in the real situation. The simluation study will show us a particular condition occurs the most likely tha other conditions. This fact enables us to obtain the Morre-Penrose inverse with less computational efforts and computational storage.