Mucoepidermoid carcinoma of the lung is a very rare and potentially malignant tumor that arises from submucosal gland of the trachea and bronchi. We experienced two cases of mucoepidermoid carcinoma which was located in the left main bronchus and right intermediate bronchus. They were treated with left sleeve resection and right bilobectomy. Postoperative course was uneventful, and the followed up for each of them was 3 year and 18 months without any evidence of recurrence.