Tarsal tunnel syndrome is a complex of symptoms resulting from the compression of the posterior tibial nerve or its branches, Many disease have been previously reported in the literatures as etiological agents in tarsal tunnel syndrome. We reported a case of tarsal tunnel syndrome secondary to neurilemoma of the first branch of lateral plantar nerve. The symptoms were similar with the entrapment syndrome of the first branch of the lateral plantar nerve. Symptoms were completely relieved after operation.