The effects of water vapor on the permeation rates of oxygen and nitrogen through poly sulfone hollow-fiber membrane were investigated. The permeation rates of both 02 and $O_2$ were decreased significantly owing to the presence of water vapor. The permeation rate of oxygen with 100% relative humidity was reduced by as much as 20%, while the permeation rate of nitrogen decreased by 14% at 30 "C and 3kgf/$cm^2$ of upstream pressure. The permeation rates of $O_2$ were declined monotonously with running time and arrived at steady state values by the presence of water vapor. However, those of $N_2$ increased tentatively and then decreased to the steady state.tate.