The panel contribution analysis to reduce interior booming noise of a passenger car is carried out using both experimental method and numerical one. The accelerations of panels are measured on the outer surface of car body during operation. The acoustic characteristic of cavity is represented by two different ways. One is the acoustic transfer function obtained by experiment with reciprocal manner. The other is the boundary element model and numerical results of the model are calculated using SYSNOISE. The results from numerical method show more good agreement with measured sound pressure levels than the experimental one. Contributions of panels for interior noise are ranked and structure of the car is reinforced according to the results, which shows that the panel contribution analysis is a powerful tool to lessen structure-borne noise of passenger vehicle.