This paper presents the analytical method to evaluate the seismic responses on steam turbine-generator rotor system. Deterministic analytical methods, such as response spectrum approach, modal superposition method and direct integration method, are used to calculate the seismic response. The computer software is also developed based on the methods then can be applied to estimate the seismic safety of turbine-generator rotor system for power plants. Numerical example of a steam turbine-generator rotor system of 1007MW nuclear power plant is presented. The aseismatic performance are checked by comparing maximum seismic deflection at bearing positions with bearing clearance.