Conventional methods for assessing remaining life of critical high temperature components in fossil power plants rely on nondestructive inspection practices and accompanying life analysis based on fracture mechanics By using these conventional methods. It has been difficult to perform uninterrupted in-service inspection for life prediction. Thus, efforts have been made for developing on-line remaining life monitoring systems employing information on the shape of structures, operating variables and material properties. In thus study, a software for on-line life monitoring system which performs real-time life evaluation of a high temperature system headers was developed. The software is capable of evaluating creep and fatigue life usage from the real-time stress data calculated by using temperatures/stress transfer Green functions derived in advance for the specific headers. The major benefits of the developed software life in determining future operating schedule, inspection interval, and replacement plan by monitoring real-time life usage based on prior operating history.