This study was done to examine the relationship among psychosocial well-being, perceived health status and health promoting lifestyle practices, and to Identify those variables affecting a health promoting lifestyle. Three hundred and forty five ruddle-aged adults completed a multiple self-reported questionnaire on psychosocial well-being, perceived health status and health promoting lifestyle profile. Data analysis were conducted by using Pearson correlation coefficients, t-test, ANOVA, Scheffe test and stepwise multiple regression nth SAS program. The results are as follows : 1. The average item score for psychosocial well-being was low at 55.98, the level of perceived health status was moderate at 5.76, and health promoting lifestyle practices were low at 110.09. Among the subscales of the health promoting lifestyle profile, stress management and self-actualization were scored higher than exercise and health responsibility. 2. Performance of health promoting lifestyle was positively correlated with perceived health status and negatively correlated with psychosocial well-being. Also, negative correlations were observed between perceived health status and psychosocial well-being. 3. There were statistically significant differences for health promoting lifestyle, psychosocial well-being and perceived health status according to sociodemographic variables. The performance of health promoting lifestyle was significantly different according to education, economic status and marriage satisfaction. Psychosocial well-being was also significantly different according to education, marriage satisfaction, and exercise. Perceived health status was significantly different according to education, occupation, and economic status. 4. Perceived health status, psychosocial well-being, marriage satisfaction and level of education together explained 21.62% of varience in the performance of health promoting lifestyle. These findings help to clarify relationships among psychosocial well-being, perceived health status, and health promoting lifestyle practices in middle-aged adults. Therefore, the result of study provide clues for encouraging people to adopt healthier lifestyles and constructing alternative strategies for promoting health practices.