This paper presents a quasi-three-dimensional calculation method considered a spanwise mixing effect in a diagonal flow impeller. The effect of this spanwise mixing caused by spanwise distribution of blade loading is evaluated by a secondary flow theory. In order to verify the validity of this method, it is applied to the analysis of a diagonal flow fan designed under a vortex type of constant circumferential velocity and that of a free vortex. The comparison of the calculated result with experimental data shows a good agreement except the regions near the casing where the flow field is affected by the tip leakage flow.