This paper describes the implementation of a multi-subject, multi-channel optical telemetry system for the short range measurement of electrocardiograms (EKGs) a system which receives command signals and transmits physiological signals to the external system using LED (Light Emitting Diode) and PD (Photodiode). This system decreases the dependency of power supply voltage to the CMOS IC chips and a new enforced synchronization technique using infrared bi-directional communication has also been proposed. The telemetry IC with the size of $5.1{ imes}5.1mm^2$ has the following functions: receiving of command signal, initialization of internal state of all functional blocks, decoding of subject selection signal, time division multiplexing of 4-channel modulated physiological signals, transmission of modulated signals to external system, and auto power down control.