세가지 식품유사용매(증류수, 4% acetic acid, 20% ethanol)중의 비스페놀류(BPF, BPA, BFDGE, BADGE)를 형광검출기의 역상 HPLC와 GC/MSD에 의해 분석하는 방법을 제안하였다. 각 비스폐놀류는 $5{sim}800;{mu}g/L$의 검량선에서 상관계수 0.9998 이상이었고 검출한계는 $1.2;{mu}g$이하였다. $200;{mu}g/L$에서의 정밀도는 3.1%이하였다. 각 식품유사용매에 비스페놀류를 일정량씩 첨가하여 동시 분석하였을 때 BPF와 BPA의 회수율은 95% 이상이었고, BFDGE와 BADGE는 약 80%였으나, 개별 첨가하였 때는 BFDGE와 BADGE 회수율이 95%이상으로 증가하였다. 이 때 검출한계는 모두 $0.40;{mu}g$이하였다. Epoxy phenol, modified epoxy, epoxy ester phenol 및 thermoset vinyl의 재질로 내부 코팅한 통조림관에서 식품유사용매로 이행되는 비스페놀류는 역상 HPLC에 의한 정량과 GC/MSD로 확인하였다 모든 재질에서 3가지 식품유사용매에 의해 BPF, BFDGE, BADGE는 검출되지 않았으나 4% acetic acid와 20% ethanol에 의해 modified epoxy를 제외한 재질에서 모두 BPA가 검출되었다.
A method was presented for determination of bisphenol F(BPF), bisphenol A(BPA), bisphenol F diglycidyl ether(BFDGE) and bisphenol A diglycidyl ether(BADGE) in 3 aqueous-based food simulants (water, 4% acetic acid, 20% ethanol) by reverse-phase high performance liquid chromatography(RP-HPLC)with fluorescence detection and gas chromatography with mass selective detection(GC/MSD). All the calibration lines in the range of $5{sim}800;{mu}g/L$ had correlation coefficients greater than 0.9998 and detection limits of less than $1.2;{mu}g$ bisphenols/L. Precision at $200;{mu}g/L$ was under 3.1%. Recoveries of bisphenols simultaneously spiked to aqueous food simulants exceeded 95% for BPF and BPA but about 80% for BFDGE and BADGE. However, recoveris of BFDGE and BPADGE respectively spiked increased upto 95%. Detection limits in recovery test were less than $0.40;{mu}g$ bisphenols/L. In migration test bisphenols were determined by RP-HPLC coupled with confirmation by GC/MSD. Can coatings of epoxy phenol, modified epoxy, epoxy ester phenol and thermoset vinyl were exposed to the 3 aqueous food simulants. BPF, BFDGE and BADGE were not detected in all the can coatings but BPA was detected in 4% acetic acid and 20% ethanol in all the can coatings except modified epoxy.
