We had applied Saenggangunbitang, Gamijihwangtang, and Saenggangunbitang-Gamijihwangtang on a alcoholic liver disease patient with diabetes mellitus, Saenggangunbitang has been used to treat alcoholic liver disease and had known to have beneficial effects. Gamijihwangtang has been used to treat Yin deficiency syndrome in Orient Medicine. We observed clinical symptom, liver function, nutritional state and blood sugar. After first administration, Clinical symptom and blood sugar were improved by Gamijihwangtang medication. Alter second administration, Clinical symptom, blood sugar and liver function were improved by Saenggangunbitang-Gamijihwangtang medication. After third administration, clinical symptom and liver function were improved by Saenggangunbitang medication. It is possibly suggested that Saenggangunbitang-Gamijihwangtang medication has a therapeutic effect on alcoholic liver disease with diabetes mellitus.