Laser cladding processing allows rapid transfer of heat to the material being processed with minimum conduction into base metal, resulting in low total heat input. The effects of Nd:YAG laser cladding with wire feeding on the mechanical properties of Inconel alloy were investigated. inconel alloy is used as the material of nuclear steam generator tubing because of its mechanical properties and corrosion resistance properties. The device for Nd:YAG laser cladding with wire feeding was designed. It consists of the wire feeding system, the wire cladding system and the shielding gas system which prevents the clad layer from being oxidized. Experimental as results indicated that the wire feeding direction and position were important for laser cladding with wire feeding. The wire feeding speed should be adapted according to cladding speed for good shaping of clad layer. The effect of heat on the HAZ size can be limited and the growth of grain size of HAZ size was not serious. The hardness of clad layer and heat affected zone increased with increasing of cladding speed.