With the increased requirement for automobile noise, a design fo mufflers with higher performances becomes more important in recent days. For a design of some mufflers, it must satisfy both minimizing back pressure and maximizing sound attenuation in broad range of frequecny. Even for a simple Helmholtz resonator, an important element in a muffler, a resonator design with accurate resonant frequency is difficult if one want to consider standing waves within the cavity. In this paper, the genetic algorithm, one of the optimization technique with high capability of global fittest solution and robust convergence, is applied to the design process of mufflers. Results show that the genetic algorithm can be successfully and efficiently used to find the fittest model for both mufflers and Helmoltz resonators.