Several methods have been developed to predict the rupture time of the boiler tubes in thermal power plant. However, existing life prediction methods give very conservative value at operating stress of power plant and rupture strain cannot be well estimated. Therefore, in this study, rupture time and strain prediction method accounting for creep, corrosion and heat transfer is newly proposed and compared with the current research results. The creep damage evolves by continuous cavity nucleation and constrained cavity growth. The corrosion damage evolves by steam side and fire side corrosion. The results showed good correlation between the theoretically predicted rupture time and the current research results. And rupture strain may be well estimated by using the proposed method.