In this paper, we present the modeling of the ozone prediction system using Neuro-Fuzzy approaches. The mechanism of ozone concentration is highly complex, nonlinear, and nonstationary, the modeling of ozone prediction system has many problems and the results of prediction is not a good performance so far. The Dynamic Polynomial Neural Network(DPNN) which employs a typical algorithm of GMDH(Group Method of Data Handling) is a useful method for data analysis, identification of nonlinear complex system, and prediction of a dynamical system. The structure of the final model is compact and the computation speed to produce an output is faster than other modeling methods. In addition to DPNN, this paper also includes a Fuzzy Logic Method for modeling of ozone prediction system. The results of each modeling method and the performance of ozone prediction are presented. The proposed method shows that the prediction to the ozone concentration based upon Neuro-Fuzzy approaches gives us a good performance for ozone prediction in high and low ozone concentration with the ability of superior data approximation and self organization.