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활성탄이 토끼에서 실험적으로 유발된 결손창 치유에 미치는 영향
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  • 활성탄이 토끼에서 실험적으로 유발된 결손창 치유에 미치는 영향
  • Effect of Activated Charcoal on Wound Healing in Rabbits
저자명
조한성,정종태,연성찬
간행물명
韓國臨床獸醫學會誌= Korean journal of veterinary clinical medicine
권/호정보
2000년|17권 2호|pp.376-380 (5 pages)
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한국임상수의학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

This study was performed to investigate the effect of activated charcoal on wound healing in an experimentally induced skin wound model. Full-thickness, skin defects ($2 cm{ imes}2 cm$) were made in two different areas on the back of eight New Zealand white rabbits. Eight of 16 wounds were treated with gauze-gauze-impregnated activated charocal granules, and another eight wounds were treated with gauze-soaked saline. Wound areas were measured every other day for 2 weeks after the wound-ing. Statistical analysis was performed with the student t-test. The mean percentage of wound con- traction on the 14th day in the activated charcoal-treaded group and in the saline treated group were 93.5% and 81_7%, respectively. The mean value of tensile, strength ell the 21s1 day after wounding was,42.70{pm}0.8 kg/5cm^2$, in the activated charcoal-treated group and $1.75 {pm} 0.5 kg/5 cm^2$ in the saline treated group. Significantly reduced wound area (p<0.05) and high tensile strength value (P<0.O5) were observed in activated charcoal-treated group compared with those in the saline treated group. In summary activated charcoa1 significantly reduced the wound area an increased tensile strength in the rabbit 7kin wound model. These results suggest that application of activated charcoal in skill wounds will promote wound healing.