This paper presents the predicted results by CFD technique of air flow and contaminant distribution in a full-scale kitchen opened to a living room, ventilated by a exhaust hood. To analyze the characteristics of the indoor environment, the concept of contaminant index was defined. In this study, the locations of the gas range and the window were chosen as the parameters to investigate the indoor environment. The values of the contaminant index for several layout of the gas range and the window were calculated and compared. When the gas range is installed along the wall with specified window location, its position in relation to the wall has unnoticed effect on contaminant infer. Once the location of the gas range is fixed, the indoor air quality may deteriorate by the proximity of the window to the gas range. This is due to the shorter distance that external fresh air must travel within the kitchen before it reaches the exhaust fan.