6 sigma movement is the most prominent quality improvement methodology in practice. Measurement plays an important role in helping any organization improve quality. Therefore, the measurement systems analysis is the first step for the quality improvement of manufacturing process in 6 sigma movement. In this study, we investigate the effect of Gage Repeatability and Reproducibility(Gage R&R) in view of defect rate and process capability indices, and provide guidelines for acceptance of gage repeatability and reproducibility(%R&R) for six sigma quality.