A novel mixed-integer linear programming model for the short-term scheduling of a sequential multipurpose batch plant is addressed. First, a time slot domain to each unit is introduced. By assigning each time slot to a product, we obtain the production sequence that minimizes makespan. For multiple-unit assignment problem where a few parallel units with the same function exist, production paths are defined for the distinction of the same stage with a different unit. As a second issue, the model adapted for sequence dependent changeover is presented. For a time slot of a unit, if a product is assigned to the time slot and a different product is assigned to the adjacent time slot, the changeover time considering this situation is included. The performance of the proposed models are illustrated through two examples.