In this paper, an efficient method is proposed to place the cooling lines(CLS) and ejector pins(EPS) of mold design. The other components of mold, except CLS and EPS, can be generated automatically by batch processing. But the placements and sizes of CLS and EPS depend on the shapes of a part, so that the design works of CLS and EPS should be processed interactively. Using the pre-defined reference points, the positions of CLS and EPS can be determined interactively. By the proposed method, the interference occurred during placing CLS and EPS can be avoided, and the proper lengths of them can be calculated automatically. The information of the positions and lengths are stored in BOM database for generating a machining data. The proposed method is implemented with Unigraphics API functions and C language, tested on Unigraphics V15.