This study is to investigate the mechanical properties and the fatigue crack propagation of fire resistance steel for frame structure as the chemical composition was changed by addition of N, B and rolled end temperature was varied. We used two kinds of specimen, the one is parallel and the other is perpendicular to the rolling directions. As rolled end temperature increased, volume fraction of ferrite and pearlite decreased, but volume fraction of baintie and grain size increased. Micro-hardness decreased as rolled end temperature increased, but tensile and yield strength increased. Volume fraction of ferrite and pearlite decreased by addition of N. But volume fraction of bainite, tensile and yield strength increased. Microstructure was changed to martensite by addition of B, and tensile and yield strength increased. Fatigue life of TL direction specimen was shorter than that of LT direction specimen. There was no significant effect to fatigue crack propagation rate by addition of N and changing rolling condition, but fatigue life was increased by addition of B.