An experimentation on the on-line fault detection and diagnosis(FDD) system has been performed with HVAC system in he experimental building constructed inside the large scale environmental chamber. Personal computer with a home-made FDD program by pattern recognition method utilizing artificial neural network was connected on-line via Ether-net TCP/IP to the supervisory control server for HVAC system. The FDD program monitored the HVAC system by 1 minuted interval. The results showed that he FDD program detected the sudden or abrupt faults such s those in fans, sensors and heater, etc.