A failure probability model based on Von-Mises failure criterion and the standard normal probability function is proposed. The effects of varying boundary conditions such as nearby cavity, backfill, load cycle and corrosion on failure probability of the buried pipes are systematically investigated. The location of cavity is found to affect failure probability of buried pipeline within a certain limit. It is noted that the flexibility of backfill plays a great role to change the failure probability of buried pipeline. Furthermore, the corrosion gives less effects than other boundary conditions such as cavity, load as cavity, load cycle, and backfill to the failure probability of buried pipeline.