The real time optimal control algorithm of the DDC controller for chilled water and supply air temperature set-point of heating, ventilating, air-conditioning and refrigeration systems has been researched for minimization of the total power which is consumed by the chiller, chilled water pump and air handing unit fan. The study has been done by using TRNSYS program in order to analyze the central cooling system in terms of the environmental variables such as indoor cooling lead and wet-bulb temperature. This optimal control alogorithm saves more energy and is suitable for real time on-line control in comparison with conventional method.