Synthesis and in Vitro Antibacterial Activity of Cephalosporins with a Pyridiniume Substituent Carrying an Isoxazole Moiety at the C-3 Position

Synthesis and in Vitro Antibacterial Activity of Cephalosporins with a Pyridiniume Substituent Carrying an Isoxazole Moiety at the C-3 Position
Synthesis and in Vitro Antibacterial Activity of Cephalosporins with a Pyridiniume Substituent Carrying an Isoxazole Moiety at the C-3 Position

ㆍ 저자명: Park. Hae-Il,Choi. Hyun-Joo,Jang. Jin-Hee,Choi. Sung-Hak,Rhee. Jae-Keol,Chang. Min-Sun
ㆍ 간행물명: Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
ㆍ 권/호정보: 2001년|24권 2호|pp.89-94 (6 pages)
ㆍ 발행정보: 대한약학회
ㆍ 파일정보: 정기간행물|ENG|
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ㆍ 주제분야: 기타

이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.

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기타언어초록

Several quaternary pyridinium cephalosporin analogues were prepared analogues were Prepared and evaluated in vitro for antibacterial activity against selected Gram-positive and Cram-negative organisms. Most of the synthesized analogues were either as effective or less effective against the tested bacterial organ isms than the reference com pounds, Cefpirome and Ceftazidime.

키워드

Quaternary pyridinium cephalosporin lsoxazole moiety Anti-staphylococcal activity Anti-pseudomonal

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