For the Tailor Welded Blank sheet used fur automobile body panel, the characteristics of fatigue crack propagation behavior were studied. The thickness of specimen was machined to be same (0.9+0.9mm) and different (0.9+2.0mm). As a base test, mechanical properties around welding zone were examined. The results indicated that there were no significant decreases in mechanical properties, but hardness around welding bead is 2.3 times greater than base material. The crack propagation rate was noticeably decreased around welding line and rapidly increased as it passed by welding line. Reviewing the shape of the crack propagation, crack width around welding line was wide around the welding zone due to retardation of crack growth, but it became narrow passing welding line due to decreased toughness. Elasto-Plastic analysis was performed by finite element analysis fur explaining the test results.