The construction of the students knowledge in e-Learning systems, namely the student modeling, is a core component used to develop e-Learning systems. However, existing e-Learning systems have many problems to share the knowledge in a heterogeneous student model and a distributed knowledge base. Because the methods of the knowledge representation are different in each e-Learning systems, the accumulated knowledge cannot be used or shared without a great deal of difficulty. In order to share this knowledge, existing systems must reconstruct the knowledge bases. Consequently, we propose a new a Case Markup Language based on XML in order to overcome these problems. A distributed e-Learning systems fan have the advantage of easily sharing and managing the heterogeneous knowledge base proposed by CaseML. Moreover students can generate and share a case knowledge to use the communication protocol of agents. In this paper, we have designed and developed a CaseML by using a knowledge markup language. Furthermore, in order to construct an intelligent e-Learning systems, we have done our research based on the design and development of the intelligent agent system by using CaseML.