The response of multi-story building structures to lateral loads, mainly due to earthquake and wind, is investigated for preliminary design purposes. Emphasis is placed on structural systems consisting of rigid and braced steel frames. An attempt to gain a qualitative understanding of the influence of bending and shear stiffness distribution on the deformations of such structures is made. This is achieved by modeling the structure with a stiffness equivalent Timoshenko beam. It is observed that the conventional stiffness distribution, dictated by strength constraints, may not be the best to satisfy deflection criteria. This is particularly the case for slender structural systems with prevailing bending deformations, such as flexible braced frames. This suggests that a new approach to the design of such frames may be appropriate when serviceability governs. A pertinent strategy for preliminary design purposes is proposed.