The fatigue crack propagation characteristics were investigated on dissimilar friction weld of two kind of heat-resisting steels (STR3 and STR35) commonly used in valve materials for vehicles. A small circular artificial defect was machined to induce fatigue crack at bonded line, heat affected zone and base metal of the weld on the surface of the specimens. From the results of the experiment, the fatigue limits of the materials STR3 and STR35 were obtained to be 429.0MPa and 409.4MPa respectably. The STR35 base metal and 1.0mm HAZ specimens showed 190% and 82% higher fatigue life than STR3 base metal. And the fatigue life of 1.0mm HAZ specimen was shown 99% on STR3 and 29% on STR35 higher than that of their base metal. But the fatigue life of weld interface specimen was shown 18% on STR3 and 72% on STR35 lower than that of their base metal because of the weld interface separation.