The mulberry (Morus spp.) is an important tree in the sericultural industry because its leaves constitute the sole source of food for the Mori silkworm (Bombyx mori). Qualitative and quantitative improvements in mulberry varieties play a vital role in industrial advances. However, the perennial nature of the plants, coupled with the species prolonged juvenile period, slows this process. Plant tissue-culture techniques hale been used extensively for stock improvement. During the last thirty years, several researchers have reported success in plant regeneration from different explants types. This review describes the major findings in mulberry tissue-culture research.