When the vehicle travels in an actual road, resistance spot weldments of the vehicle structure are exposed to complex loading state. Since the fatigue strength in resistance spot weldment of vehicle body can be determined by effect of residual stresses and loading state of driving, estimating actual loading state and considering residual stress effect are needed. In this study, Fatigue stress-fatigue life relation concerned residual stress effect was obtained by thermo elastic plastic finite element analysis. And applied loading in resistance spot weldments of vehicle body was calculated by dynamic analysis. Presumption of fatigue life was performed using proposed method