In the course of seismic probabilistic risk assessment(SPRA), seismic fragility analysis(SFA) is utilized as a tool to evaluate the actual seismic capacity of structures. This paper introduces a methodology of SFA and its evaluation procedures, especially focusing on the basic fragility variables. A new definition of the response spectrum shape factor as one of the most critical basic variables is suggested. The new factor is expressed as a term of linear algebraic sum using the modal contribution factor. The efficiency of new response spectrum shape factor is evaluated and validated to use in practice through the case study of the nuclear power plant structures. The case study results show that the proposed method can be effectively applicable to multi-mode structures with composite modal damping.