This study examined the impact of preventive environmental management practices on sales growth, manufacturing and environmental performance of the US chemical manufacturing companies. In order to investigate the impact, this study examined the relationship between the degree of preventive environmental programs and sales growth, manufacturing and environmental performances. Using a cross-sectional research design to test three hypotheses. a survey questionnaire was mailed to chemical companies in the USA. To investigate the relationship between the degree of Preventive environmental programs and sales growth, manufacturing and environmental performances. t-tests were used. According to the results of t-tests the higher preventive implementation programs achieved better manufacturing and environmental performances than lower preventive or reactive strategies. But there was no difference in sales growth between tow groups.