In order to study the change of pollution loads flowing into Mokpo harbour after the operation of Mokpo Municipal Sewage Treatment Plant (MMSTP) and to evaluate the contribution of MMSTP operation to the improvement of marine water quality of Mokpo harbour, the pollution loads flowing into Mokpo harbour from land in dry weather were surveyed and estimated on the bases of the seasonal flow rates and the seasonal water qualities of streams and effluents located around Mokpo harbour from summer, 1997 to spring, 1998 before the operation of MMSTP, and the pollution loads of the inflow and the effluent of MMSTP were also surveyed and estimated from winter, 1998 to spring, 1999 after the operation of MMSTP. The treatment rates of MMSTP were shown to be about 49% in COD, 76% in TSS, 79% in VSS, 3% in T-N, 7% in DIP, 29% in T-P and -32% in DIN. The change rates of pollution loads flowing into the inner harbour of Mokpo due to the operation of MMSTP were shown to be about 56% In COD, 78% in TSS, 84% in VSS, 45% in DIN, 22% in T-N, 34% in T-P and -14% in DIP. The contribution rates of MMSTP operation to the reduction of total pollution loads flowing into the entire Mokpo harbour were found to be about 3% in COD, 3% in 755,5% in VSS,1% in DIP, 3% in T-P and -1% in DIN.