Library and information science(LIS) research has been dominated by functionalistic orientation as one of the postulates of positivism. As a result, it has often been criticized that LIS research does not take into account the social, cultural, political, and economic contexts on which the theories and the practices of LIS are based. In this regard, this paper seeks to establish and apply critical inquiry through a review of the relevant aspects of critical theory and application of those insights to current research and practice in LIS. Connections of LIS research to relevant political, social and economic issues are particularly stressed.