The fault detection and diagnosis technology may be applied in order to decrease the energy consumption and the maintenance cost of the air-conditioning system. In this study, two different types of faults in the air-conditioning system, such as the condenser fouling and the evaporator fan slowdown, were considered. The neural network algorithm combined with data preprocessor was developed and applied to detect the faults of the real system. Test results show that this method is very effective to detect the faults in the air-conditioning system. Therefore, this developed method can be used for the development of the air-conditioner fault detection system.