The purpose of this study was to review the knowledge related to historic background, causes, symptoms, etiology and rehabilitation methods related to this disease and suggest some ways to reduce complications from it. The importance of underwater pressure disease was not emphasized, therefore, there is a need for continuous research on treatment methods and prevention for it. As one goes into the deeper water, they will be affected by the hydraulic pressure rather then the atmospheric pressure, and it will be increased 1mmHg by 10meters. Underwater pressure disease can be occurred when one comes out of deeper water too quicked. This results the imbalance of the composition rate of nitrogen in blood. However, there is not enough facilities to treat this disease and these facilities are located in limited areas. Therefore, there is an urgent need to set up a medial center that is specialized in prevention and treatment of underwater pressure disease.