In this paper, we propose an expert system for electronic interlocking which enhances the safty, efficiency and expanability of the existing system by designing real-time interlocking control based on the interlocking table automatically generated using artificial intelligence approach. The expert system consists of two parts; an interlocking table generation part and a real-time interlocking control part. The former generates automatically the interlocking relationship of all possible routes by searching dynamically the station topology which is obtained from station database. On the other hand, the latter controls the status of station facilities in real-time by applying the generated interlocking relationship to the signal facilities such as signal devices, points, track circuits for a given route. The expert system is implemented in C language which is suitable to implement the interlocking table generation part using the dynamic memory allocation technique. Finally, the effectiveness of the expert system is proved by simulating for the typical station model.