- 항혈관 1호의 항전이에 관한 연구
- ㆍ 저자명
- 손창규,조종관,이승호,Son. Chang Kyu,Cho. Chong Kwan,Lee. Seung ho
- ㆍ 간행물명
- 동의생리병리학회지
- ㆍ 권/호정보
- 2002년|16권 1호|pp.133-140 (8 pages)
- ㆍ 발행정보
- 대한동의생리학회
- ㆍ 파일정보
- 정기간행물| PDF텍스트
- ㆍ 주제분야
- 기타
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To evaluate the anti metastatic effect of Antivascular-first(AntiV-F), we investigated cytotoxic effect on B16-F10 and HMCB. gene expression of MMP-9 and nm23-H1, and survival. After treating with AntiV-F, AntlV-F promoted cytotoxic effect on B16-F10 and HMCB as its density, compared with Control. AntiV-F inhibited gene expression of MMP-9 in the L+14 and HMCB cell line compared with Control. On the other hand AntiV-F increases gene expression of nm23-H1 and survival about 30% compared with Control. These results suggest that AntiV-F has effects on anti-metastasis can be used for treatment of cancer patients and preventing recurrence.