This paper presents the development of an Intelligent Cavity Layout Design System (ICLDS) for multiple cavity injection moulds. The system is intended to assist mould designers in cavity layout design at concept design stage. The complexities and principles of cavity layout design as well as various dependencies in injection mould design are introduced. The knowledge in cavity layout design is summarized and classified. The functionality, the overall structure and general process of ICLDS are explained. The paper also discusses such issues as knowledge representation and case-based reasoning used in the development of the system. The functionality of the system is illustrated with an example of cavity layout design problem.