The differential quadrature method (DQM) is a numerical technique of rather recent origin, which by its continually increasing applications in different problems of engineering, is a competing alternative to the conventional numerical techniques for the solution of initial and boundary value problems. The work of this paper concerns the application of the DQM in the area of the buckling of multi layered orthotropic composite plates with various boundary conditions the buckling of multi layered composite plates with constant and variable thickness under axial compressive static loading is considered. The effects of fiber orientation and boundary conditions on static behavior of composite plates are presented. The comparison of results from the present method and those obtained from NISA II software shows the accuracy and reliability of this method.