Osteogenic sarcoma is the most common primary malignant tumor of bone in which tumor cells form neoplastic osteoid or bone or both. Classic osteogenic sarcoma usually involves the metaphysis of the more rapidly growing long bones (distal femur, proximal tibia). Osteogenic sarcoma of the foot is rarely noted and only a few well documented cases have been reported. Osteogenic sarcoma of foot can clinically, radiographically, and histologically mimic several benign lesions and tumor-like lesions, so it sometimes leads to late diagnosis and delayed treatment. We experienced a case of primary osteogenic sarcoma on left calcaneus in 66-years-old female and report it with a review of references.