The acute osteomyelitis of calcaneus has been rarely reported. A diabetic patient, 44 year-old male was appeared with painful swelling on the hindfoot after being injected with steroid on the lateral area of hindfoot at a private clinic. The diagnosis was an acute calcaneal osteomyelits which was based on MRI finding. We report a case of the acute osteomyelitis of calcaneus, which was successfully treated with the curettage, antibiotic- impregnated bone cement beads, and delayed autogenous iliac bone graft, using the lateral approach.