The International Space Station (ISS) is being jointly developed by the following 16 international partners: The United States, Russia, Japan, Canada, Brazil, and the 11 member states of the European Space Agency. Assembly of ISS is a large-scale international program which commenced in November 1998, and is expected to conclude in 2006. Korea Aerospace Research Institute (KARI) is making effort to take part in the development of Payload Support & Interface Module (PSIM) for ISS. When success is achieved with ISS PSIM development project, Korea will have the rights to utilize external attached payload sites and research activities on ISS. Therefore preparation for the utilization of ISS EXPRESS pallet, JEM-EF, and Columbus-EPF need to be made. This paper shows the investigation results of the external attached payload sites for ISS and the application field of space and Earth science.