The economic and environmental friendliness analysis of the nuclear fuel cycle options that can be expected in Korea were performed. Options considered are direct disposal, reprocessing and DUPIC (Direct Use of Spent PWR Fuel In CANDU Reactors). By considering the result of calculation of the annual uranium requirement and nuclear spent fuel generation by analysis of nuclear fuel material flows in the nuclear fuel cycle options, we decided the time of back-end nuclear fuel cycle processes and the volume. Then we can analyze the economic and environmental friendliness by applying the unit cost and unit value of each process, respectively.