This case study was performed to assess the effectiveness of taping therapy for the patient who have patellofemoral joint pain during knee extension exercise. The results were as follows: 1. Pain degree of VAS was decreased at every taping therapy. 2. A number of knee extension was increased at every taping therapy. 3. Diameter of quadriceps was increased at every taping therapy. 4. Pattern of gait was normalized at every taping therapy. We found improve of pain degree, a number of knee extension, diameter of quadriceps, and pattern of gait. These results are imply that taping therapy may have effectiveness to those who have patellofemoral joint pain during knee extension exercise.