The purpose of study was to compare change of blood volume on upper limb of stimulus site on interferential current therapy. Twenty university student(twelve females. eight males :mean aged 23.08) with health condition participated this study MP150 system(biopac system) was used to measured blood volume. PPG senser was located thrum finger end The obtain result are as follows. 1. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 2. The result of this study were following that stimulate time blood volume were significantly increased sympathetic stimulation group compared with muscle stimulation group(p<.05). 3. The result of this study were following that sympathetic stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05). 4. The result of this study were following that muscle stimulation group were significantly increased stimulate time blood volume compared with stimulate time blood volume(p<.05).