Boiling heat transfer coefficients and pressure drops for R-22 and R-407C were measured in horizontal micro-channels. The test section is stainless steel tube, inner tube diameters are 1.8mm and 2.8mm, and the respective lengths are 1500mm and 3000mm. The range of mass flux is 300-600kg/$m^2$s and heat flux is 5-15kW/$m^2$. In this results, pressure drop increased linearly for both R-22 and R-407C with increased mass flux, but the increase of heat flux did not affect the pressure. In addition, the pressure drop was fairly increased in the high quality region rather than low quality region. In the range of low quality, the mass flux had a small affect on the heat transfer coefficients, however, in high quality region, the heat transfer coefficients increased even more with increasing mass flux. Under the low quality region and low mass flux, the heat transfer coefficients increased with increasing heat flux densities. The effects of inner tube diameter were clearly observed. Namely, the measured pressure drop inside inner tube diameter 1.8 mm is higher than 2.8 mm with increasing the mass flux and heat flux. Also, the measured local heat transfer coefficient inside inner tube diameter 1.8 mm is higher than 2.8 mm in the range of high qualities. The experimental data for R-407C compared with proposed correlation using pure refrigerant. The experimental data for R-407C was more decreased than the proposed correlation for pure refrigerant up to 50% or more.